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Patient Education & Wellness Resources

| Your Best Life Medical eClinic

Helpful health information for adults in Virginia, including telehealth care tips, common condition education, prevention guidance, and wellness support from Your Best Life Medical eClinic.

Could Your Fatigue, Weight Gain, or Brain Fog Be Hypothyroidism?

Feb 21
3 min read


Hypothyroidism, also called an underactive thyroid, happens when the thyroid gland does not make enough thyroid hormone for the body’s needs. Because thyroid hormone helps regulate energy use throughout the body, low thyroid levels can affect energy, weight, mood, digestion, skin, hair, heart rate, menstrual cycles, and temperature tolerance.


Hypothyroidism can develop slowly, and symptoms may be easy to miss or mistake for stress, aging, poor sleep, depression, menopause, or a busy lifestyle. A medical evaluation can help determine whether thyroid testing is appropriate.


What is hypothyroidism?

The thyroid is a small butterfly-shaped gland in the front of the neck. It makes hormones that help regulate metabolism, energy, body temperature, heart function, digestion, and many other body processes.


When thyroid hormone levels are too low, body functions may slow down. This can lead to symptoms such as fatigue, cold intolerance, constipation, dry skin, weight changes, and low mood.


Common causes

Common causes or contributing factors may include:

  • Hashimoto’s thyroiditis, an autoimmune thyroid condition

  • Family history of thyroid disease

  • Prior thyroid surgery

  • Prior radioactive iodine treatment

  • Radiation exposure to the neck

  • Certain medications

  • Iodine imbalance

  • Pregnancy or postpartum thyroid changes

  • Pituitary gland disorders, less commonly

  • Other autoimmune conditions


Hashimoto’s thyroiditis is one of the most common causes of hypothyroidism in the United States.


Common symptoms

Hypothyroidism symptoms may include:

  • Fatigue

  • Weight gain or difficulty losing weight

  • Feeling cold when others are comfortable

  • Constipation

  • Dry skin

  • Hair thinning or hair loss

  • Brittle nails

  • Puffy face

  • Hoarse voice

  • Muscle aches or weakness

  • Joint pain or stiffness

  • Low mood or depression symptoms

  • Brain fog or forgetfulness

  • Slower heart rate

  • Heavy or irregular menstrual periods

  • Fertility concerns

  • Elevated cholesterol

  • Low energy or reduced exercise tolerance


Not everyone has all symptoms. Some people have mild symptoms or no obvious symptoms, especially early on.


Risk factors

Hypothyroidism may be more likely in people who have:

  • Family history of thyroid disease

  • Autoimmune disease, such as type 1 diabetes or celiac disease

  • History of thyroid surgery

  • Prior radiation to the head or neck

  • Prior radioactive iodine treatment

  • Pregnancy or recent childbirth

  • Age over 60

  • Certain medication exposure

  • Known thyroid antibodies

  • History of abnormal thyroid labs


Women are diagnosed with hypothyroidism more often than men, but anyone can develop it.


When to seek medical care

Schedule a medical evaluation if you have:

  • Persistent fatigue

  • Unexplained weight gain

  • Difficulty losing weight despite consistent effort

  • Feeling unusually cold

  • Constipation that is persistent or worsening

  • Hair thinning or hair loss

  • Dry skin with other thyroid-type symptoms

  • Heavy, irregular, or changing periods

  • Fertility concerns

  • Depression symptoms or brain fog

  • Elevated cholesterol

  • Family history of thyroid disease

  • History of thyroid disease or abnormal thyroid labs

  • New symptoms after pregnancy

  • Neck swelling, thyroid enlargement, or a lump in the neck


Thyroid symptoms can overlap with anemia, vitamin deficiencies, diabetes, depression, sleep apnea, menopause, medication side effects, and other medical concerns, so evaluation is important.


When to seek urgent or emergency care

Seek urgent or emergency care for:

  • Severe weakness

  • Confusion

  • Fainting

  • Chest pain

  • Trouble breathing

  • Very slow heart rate with symptoms

  • Low body temperature

  • Severe swelling

  • Severe allergic reaction symptoms

  • Rapidly worsening symptoms

  • Thoughts of self-harm or suicide


Call or text 988 for mental health crisis support. Call 911 for a medical emergency.


Can telehealth help?

Yes. Telehealth may help review symptoms, medical history, family history, medications, weight changes, menstrual changes, mood symptoms, and whether thyroid-related labs may be appropriate.


Telehealth may also help review thyroid lab results and discuss whether follow-up, repeat testing, medication review, or in-person evaluation may be needed.


In-person care may be needed for a neck lump, significant thyroid enlargement, severe symptoms, pregnancy-related concerns, abnormal exam findings, or symptoms that suggest an urgent condition.


Prevention and follow-up

General prevention and follow-up considerations include:

  • Following up on abnormal thyroid labs

  • Reviewing thyroid symptoms when fatigue, weight changes, mood changes, or menstrual changes occur

  • Keeping a personal record of thyroid results if you have known thyroid disease

  • Reviewing medication and supplement use with a healthcare professional

  • Avoiding unregulated thyroid supplements without medical guidance

  • Monitoring thyroid levels during pregnancy or postpartum when indicated

  • Keeping follow-up appointments if thyroid medication is prescribed

  • Reporting symptoms that suggest over-treatment or under-treatment


Thyroid hormone levels can change over time, so follow-up testing and monitoring may be needed when thyroid disease is suspected or diagnosed.


Final thought

Hypothyroidism can cause fatigue, weight changes, cold intolerance, constipation, dry skin, hair thinning, mood changes, and brain fog, but these symptoms can also have other causes. A medical evaluation and appropriate lab testing can help clarify whether the thyroid may be part of the problem.



This information is for educational purposes only and does not replace medical advice, diagnosis, or treatment. If you are experiencing severe symptoms, signs of infection, severe allergic reaction symptoms, trouble breathing, or a medical emergency, call 911 or go to the nearest emergency room.

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